KLF10/TIEG1 antibody

Catalog No. ABIN7115728

This Rabbit Polyclonal antibody specifically detects KLF10/TIEG1 in WB, ELISA, IP and IF. It exhibits reactivity toward Human.

Quick Overview for KLF10/TIEG1 antibody (ABIN7115728)

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF10/TIEG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-KLF10/TIEG1 Antibody

Purpose: KLF10 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Kruppel-like factor 10

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for KLF10/TIEG1

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Alternative Name: KLF10

Background:

Synonyms: Krueppel-like factor 10|EGR-alpha|Transforming growth factor-beta-inducible early growth response protein 1 (TGFB-inducible early growth response protein 1, TIEG-1)|KLF10|TIEG|TIEG1

Background: Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock, binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis(By similarity). May play a role in the cell cycle regulation.

Molecular Weight: 52 kDa

Gene ID: 7071

UniProt: Q13118

Pathways: Stem Cell Maintenance