MPP5 antibody

Catalog No. ABIN7116195

The Rabbit Polyclonal anti-MPP5 antibody (ABIN7116195) specifically detects MPP5 in WB, ELISA and IP. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MPP5 antibody (ABIN7116195)

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-MPP5 Antibody

Purpose: PALS1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: membrane protein, palmitoylated 5(MAGUK p55 subfamily member 5)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MPP5

Target: MPP5 (Membrane Protein, Palmitoylated 5 (MAGUK P55 Subfamily Member 5) (MPP5))

Alternative Name: PALS1

Background:

Synonyms: Protein PALS1|MAGUK p55 subfamily member 5|Membrane protein, palmitoylated 5|Protein associated with Lin-7 1|PALS1|MPP5

Background: May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton(By similarity).

Molecular Weight: 70-75 kDa

Gene ID: 64398

UniProt: Q8N3R9

Pathways: Nucleotide Phosphorylation, Tube Formation, Asymmetric Protein Localization