RIOX2 antibody

Catalog No. ABIN7116550

This Rabbit Polyclonal antibody specifically detects RIOX2 in ELISA, WB, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RIOX2 antibody (ABIN7116550)

Target: RIOX2 (Ribosomal Oxygenase 2 (RIOX2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIOX2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-RIOX2 Antibody

Purpose: RIOX2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: MYC induced nuclear antigen

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RIOX2

Target: RIOX2 (Ribosomal Oxygenase 2 (RIOX2))

Alternative Name: RIOX2

Background:

Synonyms: Ribosomal oxygenase 2|60S ribosomal protein L27a histidine hydroxylase|Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA|Histone lysine demethylase MINA|MYC-induced nuclear antigen|Mineral dust-induced gene protein|Nucleolar protein 52|Ribosomal oxygenase MINA (ROX)|RIOX2|MDIG|MINA|MINA53|NO52

Background: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3(H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

Molecular Weight: 53 kDa

Gene ID: 84864

UniProt: Q8IUF8