NUP85 antibody

Catalog No. ABIN7117054

This Rabbit Polyclonal antibody specifically detects NUP85 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for NUP85 antibody (ABIN7117054)

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP85 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NUP85 Antibody

Purpose: NUP85 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nucleoporin 85kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NUP85

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Alternative Name: NUP85

Background:

Synonyms: Nuclear pore complex protein Nup85|85 kDa nucleoporin|FROUNT|Nucleoporin Nup75|Nucleoporin Nup85|Pericentrin-1|NUP85|NUP75|PCNT1

Background: Essential component of the nuclear pore complex(NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Molecular Weight: 70-75 kDa

Gene ID: 79902

UniProt: Q9BW27