SLCO4C1 antibody

Catalog No. ABIN7117131

This anti-SLCO4C1 antibody is a Rabbit Polyclonal antibody detecting SLCO4C1 in WB, ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for SLCO4C1 antibody (ABIN7117131)

Target: SLCO4C1 (OATP-H) (Organic Anion Transporter H (OATP-H))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLCO4C1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SLCO4C1 Antibody

Purpose: Slco4c1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: solute carrier organic anion transporter family, member 4C1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SLCO4C1

Target: SLCO4C1 (OATP-H) (Organic Anion Transporter H (OATP-H))

Alternative Name: Slco4c1

Background:

Synonyms: Solute carrier organic anion transporter family member 4C1 (Slco4c1)|Oatp-R|Organic anion transporting polypeptide 4C1 (OATP4C1)|Solute carrier family 21 member 20|Slco4c1|Oatp4c1|Slc21a20

Background: Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.

Molecular Weight: 80 kDa

Gene ID: 227394

UniProt: Q8BGD4