P-Glycoprotein antibody

Catalog No. ABIN7117181

The Rabbit Polyclonal anti-P-Glycoprotein antibody has been validated for WB, IHC, IP and ELISA. It is suitable to detect P-Glycoprotein in samples from Human and Mouse.

Quick Overview for P-Glycoprotein antibody (ABIN7117181)

Target: P-Glycoprotein

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P-Glycoprotein antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA

Product Details anti-P-Glycoprotein Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ABCB1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IP: 1:200-1:1000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for P-Glycoprotein

Target: P-Glycoprotein

Alternative Name: P Glycoprotein

Background: Synonyms:ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1 Background:ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

Molecular Weight: 142 kDa

Gene ID: 5243

UniProt: P08183