PHOX2B antibody (AA 60-314)

Catalog No. ABIN7117203

This anti-PHOX2B antibody is a Mouse Monoclonal antibody detecting PHOX2B in WB, ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for PHOX2B antibody (AA 60-314) (ABIN7117203)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 2B0

Product Details anti-PHOX2B Antibody

Binding Specificity: AA 60-314

Purpose: PHOX2B antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 60-314aa

Immunogen: paired-like homeobox 2b

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHOX2B

Background:

Synonyms: Paired mesoderm homeobox protein 2B|Neuroblastoma Phox (NBPhox)|PHOX2B homeodomain protein|Paired-like homeobox 2B|PHOX2B|PMX2B

Background: Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Molecular Weight: 35 kDa

Gene ID: 8929

UniProt: Q99453