PKD2L1 antibody

Catalog No. ABIN7117651

This Rabbit Polyclonal antibody specifically detects PKD2L1 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PKD2L1 antibody (ABIN7117651)

Target: PKD2L1 (Polycystic Kidney Disease 2-Like 1 (PKD2L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD2L1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PKD2L1 Antibody

Purpose: PKD2L1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polycystic kidney disease 2-like 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PKD2L1

Target: PKD2L1 (Polycystic Kidney Disease 2-Like 1 (PKD2L1))

Alternative Name: PKD2L1

Background:

Synonyms: Polycystin-2-like protein 1 (Polycystin-2L1)|Polycystic kidney disease 2-like 1 protein|Polycystin-2 homolog|Polycystin-L|Polycystin-L1|PKD2L1|PKD2L|PKDL|TRPP3

Background: Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells, however, its contribution to sour taste perception is unclear in vivo and may be indirect.

Molecular Weight: 92 kDa

Gene ID: 9033

UniProt: Q9P0L9