RASIP1 antibody

Catalog No. ABIN7118312

The Rabbit Polyclonal anti-RASIP1 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect RASIP1 in samples from Human, Rat and Mouse.

Quick Overview for RASIP1 antibody (ABIN7118312)

Target: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RASIP1 Antibody

Purpose: RASIP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Ras interacting protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RASIP1

Target: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Alternative Name: RASIP1

Background:

Synonyms: Ras-interacting protein 1 (Rain)|RASIP1

Background: Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells(By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Molecular Weight: 115 kDa

Gene ID: 54922

UniProt: Q5U651