Riboflavin Kinase antibody

Catalog No. ABIN7118514

This anti-Riboflavin Kinase antibody is a Rabbit Polyclonal antibody detecting Riboflavin Kinase in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Riboflavin Kinase antibody (ABIN7118514)

Target: Riboflavin Kinase (RFK)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Riboflavin Kinase antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Riboflavin Kinase Antibody

Purpose: RFK antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: riboflavin kinase

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Riboflavin Kinase

Target: Riboflavin Kinase (RFK)

Alternative Name: RFK

Background:

Synonyms: Riboflavin kinase|ATP:riboflavin 5'-phosphotransferase|Flavokinase|RFK

Background: Catalyzes the phosphorylation of riboflavin(vitamin B2) to form flavin-mononucleotide(FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species(ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.

Molecular Weight: 18 kDa

Gene ID: 55312

UniProt: Q969G6