SAMHD1 antibody

Catalog No. ABIN7118779

This Rabbit Polyclonal antibody specifically detects SAMHD1 in WB, ELISA, IHC, FACS and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SAMHD1 antibody (ABIN7118779)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-SAMHD1 Antibody

Purpose: SAMHD1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SAM domain and HD domain 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Background:

Synonyms: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase)|Dendritic cell-derived IFNG-induced protein (DCIP)|Monocyte protein 5 (MOP-5)|SAM domain and HD domain-containing protein 1 (hSAMHD1)|SAMHD1|MOP5

Background: Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.

Molecular Weight: 64-72 kDa

Gene ID: 25939

UniProt: Q9Y3Z3