SERPINC1 antibody (AA 1-259)

Catalog No. ABIN7118893

This Mouse Monoclonal antibody specifically detects SERPINC1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SERPINC1 antibody (AA 1-259) (ABIN7118893)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SERPINC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 9A4

Product Details anti-SERPINC1 Antibody

Binding Specificity: AA 1-259

Purpose: SERPINC1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-259aa

Immunogen: serpin peptidase inhibitor, clade C(antithrombin), member 1

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: SERPINC1

Background:

Synonyms: Antithrombin-III (ATIII)|Serpin C1|SERPINC1|AT3

Background: SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Molecular Weight: 53 kDa

Gene ID: 462

UniProt: P01008