SERPINH1 antibody

Catalog No. ABIN7118960

The Rabbit Polyclonal anti-SERPINH1 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect SERPINH1 in samples from Human and Mouse.

Quick Overview for SERPINH1 antibody (ABIN7118960)

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SERPINH1 Antibody

Purpose: SERPINH1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SERPINH1

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Alternative Name: SERPINH1

Background:

Synonyms: Serpin H1|47 kDa heat shock protein|Arsenic-transactivated protein 3 (AsTP3)|Cell proliferation-inducing gene 14 protein|Collagen-binding protein (Colligin)|Rheumatoid arthritis-related antigen RA-A47|SERPINH1|CBP1|CBP2|HSP47|SERPINH2

Background: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Molecular Weight: Refer to figures

Gene ID: 871

UniProt: P50454