SMYD3 antibody

Catalog No. ABIN7118984

The Rabbit Polyclonal anti-SMYD3 antibody has been validated for WB, IHC, ELISA and IP. It is suitable to detect SMYD3 in samples from Human, Mouse and Rat.

Quick Overview for SMYD3 antibody (ABIN7118984)

Target: SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMYD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-SMYD3 Antibody

Purpose: SMYD3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SET and MYND domain containing 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SMYD3

Target: SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Alternative Name: SMYD3

Background:

Synonyms: Histone-lysine N-methyltransferase SMYD3|SET and MYND domain-containing protein 3|Zinc finger MYND domain-containing protein 1|SMYD3|ZMYND1|ZNFN3A1

Background: Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di-and tri-methylation, but not monomethylation(PubMed:15235609, PubMed:22419068). Also methylates 'Lys-5' of histone H4(PubMed:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex(PubMed:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences(PubMed:15235609).

Molecular Weight: 42-45 kDa

Gene ID: 64754

UniProt: Q9H7B4