SCUBE3 antibody

Catalog No. ABIN7119062

The Rabbit Polyclonal anti-SCUBE3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect SCUBE3 in samples from Human, Mouse and Rat.

Quick Overview for SCUBE3 antibody (ABIN7119062)

Target: SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCUBE3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SCUBE3 Antibody

Purpose: SCUBE3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: peptide, aa450-aa550

Immunogen: signal peptide, CUB domain, EGF-like 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SCUBE3

Target: SCUBE3 (Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3))

Alternative Name: SCUBE3

Background:

Synonyms: Signal peptide, CUB and EGF-like domain-containing protein 3|SCUBE3|CEGF3

Background: Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.

Molecular Weight: 130 kDa

Gene ID: 222663

UniProt: Q8IX30