ST3GAL3 antibody

Catalog No. ABIN7119479

The Rabbit Polyclonal anti-ST3GAL3 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect ST3GAL3 in samples from Human, Mouse and Rat.

Quick Overview for ST3GAL3 antibody (ABIN7119479)

Target: ST3GAL3 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 3 (ST3GAL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST3GAL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ST3GAL3 Antibody

Purpose: ST3GAL3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ST3 beta-galactoside alpha-2, 3-sialyltransferase 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ST3GAL3

Target: ST3GAL3 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 3 (ST3GAL3))

Alternative Name: ST3GAL3

Background:

Synonyms: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase|Beta-galactoside alpha-2,3-sialyltransferase 3 (Alpha 2,3-ST 3)|Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|ST3Gal III (ST3GalIII)|ST3N|Sialyltransferase 6|ST3GAL3|SIAT6

Background: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene.

Molecular Weight: 50 kDa

Gene ID: 6487

UniProt: Q11203

Pathways: Glycosaminoglycan Metabolic Process