TTF1 antibody

Catalog No. ABIN7120079

The Mouse Monoclonal anti-TTF1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect TTF1 in samples from Human.

Quick Overview for TTF1 antibody (ABIN7120079)

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TTF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4D3

Product Details anti-TTF1 Antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NK2 homeobox 1

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Alternative Name: TTF1

Background: Synonyms:BHC, Homeobox protein Nkx 2.1, NK 2, NK2 homeobox 1, NKX2 1, NKX2.1, NKX2-1, NKX2A, TEBP, Thyroid nuclear factor 1, Thyroid transcription factor 1, TITF1, TTF 1, TTF1 Background:Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.

Molecular Weight: 42 kDa

Gene ID: 7270

UniProt: Q15361

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour