TYW1B antibody

Catalog No. ABIN7120318

This Rabbit Polyclonal antibody specifically detects TYW1B in IHC, WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TYW1B antibody (ABIN7120318)

Target: TYW1B (tRNA-YW Synthesizing Protein 1 Homolog B (S. Cerevisiae) (TYW1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYW1B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-TYW1B Antibody

Purpose: TYW1B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tRNA-yW synthesizing protein 1 homolog B(non-protein coding)

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TYW1B

Target: TYW1B (tRNA-YW Synthesizing Protein 1 Homolog B (S. Cerevisiae) (TYW1B))

Alternative Name: TYW1B

Background:

Synonyms: S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B|Radical S-adenosyl methionine and flavodoxin domain-containing protein 2|tRNA wybutosine-synthesizing protein 1 homolog B|TYW1B|RSAFD2

Background: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis(By similarity).

Molecular Weight: 77 kDa

Gene ID: 441250

UniProt: Q6NUM6