VAMP7 antibody

Catalog No. ABIN7120761

This anti-VAMP7 antibody is a Rabbit Polyclonal antibody detecting VAMP7 in ELISA, WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for VAMP7 antibody (ABIN7120761)

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAMP7 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-VAMP7 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vesicle-associated membrane protein 7

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200,IF: 1:10-1:100, IP: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for VAMP7

Target: VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Alternative Name: VAMP7/TI-VAMP

Background: Synonyms:SYBL1, Synaptobrevin like protein 1, Tetanus insensitive VAMP, TI VAMP, TI-VAMP, VAMP 7, VAMP7 Background:VAMP7, also named as SYBL1 and TI-VAMP, belongs to the synaptobrevin family. It is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. VAMP7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. It is required for calcium regulated lysosomal exocytosis. VAMP7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. It is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. It is also required for focal exocytosis of late endocytic vesicles during phagosome formation. The antibody is specific to VAMP7.

Molecular Weight: 20 kDa, 50 kDa

UniProt: P51809