Vitamin D-Binding Protein antibody

Catalog No. ABIN7120780

This Mouse Monoclonal antibody specifically detects Vitamin D-Binding Protein in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Vitamin D-Binding Protein antibody (ABIN7120780)

Target: Vitamin D-Binding Protein (GC)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Vitamin D-Binding Protein antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2H10

Product Details anti-Vitamin D-Binding Protein Antibody

Purpose: Vitamin D binding protein antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: group-specific component(vitamin D binding protein)

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Vitamin D-Binding Protein

Target: Vitamin D-Binding Protein (GC)

Alternative Name: Vitamin D binding protein

Background:

Synonyms: Vitamin D-binding protein (DBP, VDB)|Gc protein-derived macrophage activating factor (Gc-MAF, GcMAF)|Gc-globulin|Group-specific component (Gc)|Vitamin D-binding protein-macrophage activating factor (DBP-maf)|GC

Background: Vitamin D binding protein is a sparsely glycosylated serum protein responsible for highly specific binding and tissue-specific delivery of vitamin D and its metabolites. In addition, it is also an actin scavenger, and is the precursor to the immunomodulatory protein, Gc-MAF. Vitamin D binding protein has been proposed to have significant roles in C5a chemotaxis, osteoclast development and possibly in macrophage activation/recruitment.

Molecular Weight: 53 kDa

Gene ID: 2638

UniProt: P02774

Pathways: Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process