PFKFB1 antibody (AA 21-120)

Catalog No. ABIN708236

The Rabbit Polyclonal anti-PFKFB1 antibody has been validated for WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro). It is suitable to detect PFKFB1 in samples from Mouse.

Quick Overview for PFKFB1 antibody (AA 21-120) (ABIN708236)

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKFB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PFKFB1 Antibody

Binding Specificity: AA 21-120

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PFKFB1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PFKFB1

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Alternative Name: PFKFB1

Background:

Synonyms: 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 1, 6-bisphosphatase, 6-P2ase 1, 6-P2ASE liver isozyme, 6PF 2 K/Fru 2 6 P2ASE liver isozyme, 6PF 2 K/Fru 2,6 P2ase 1, 6PF-2-K/Fru-2, F261_HUMAN, F6PK, Fructose 2 6 bisphosphatase, Fructose 6 phosphate 2 kinase:fructose 2 6 bisphosphatase, Fructose-2, HL2K, MGC116715, MGC116717, PFK/FBPase 1, PFKFB 1, Pfkfb1, PFRX.

Background: PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. It forms a homodimer that is involved in both the synthesis and degradation of fructose 2,6-bisphosphate. The activity of this enzyme is thought to regulate glucose homeostasis.

Gene ID: 5207

Pathways: Regulation of Carbohydrate Metabolic Process