ETS2 antibody
-
- Target See all ETS2 Antibodies
- ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This ETS2 antibody is un-conjugated
-
Application
- ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Coating (Coat)
- Specificity
- ETS2 (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human ETS2 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product ETS2 Primary Antibody
-
-
- Application Notes
-
Known_Application: ELISA (For coating, order antibody without BSA), ,Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Optimal dilution for a specific application should be determined.
Positive_Control: Human thymus, lung or cerebellum.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
-
- Target
- ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
- Alternative Name
- ETS2 (ETS2 Products)
- Synonyms
- 0123/09 antibody, 0608/07 antibody, 0998/12 antibody, 3520 antibody, CG17077 antibody, CG8705 antibody, D-Ets-2 antibody, D-ets-2 antibody, DMPOINT1A antibody, Dmel\\CG17077 antibody, E(E2F)3D antibody, EK3-2 antibody, ETS2 antibody, EY3-1 antibody, Ets antibody, Ets2 antibody, Ets58AB antibody, Ets94F antibody, PNT-P1 antibody, PNTP1 antibody, PNTP2 antibody, POINT antibody, Pnt antibody, Pnt-P1 antibody, PntP1 antibody, PntP2 antibody, Pointed-P1 antibody, ets94F antibody, l(3)07825 antibody, l(3)j1B7 antibody, l(3)s118306 antibody, png antibody, pnt-P1 antibody, pnt-P2 antibody, pntP2 antibody, pntegfr antibody, pointed-RC antibody, ptd antibody, zgc:92106 antibody, wu:fe02h08 antibody, wu:fk74c05 antibody, AU022856 antibody, Ets-2 antibody, ETS2IT1 antibody, c-ets-2 antibody, pointed antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antibody, E26 avian leukemia oncogene 2, 3' domain antibody, ETS proto-oncogene 2, transcription factor antibody, pnt antibody, ets2 antibody, Ets2 antibody, ETS2 antibody
- Background
-
C ets 2 protein, ETS2, ETS2IT1, Oncogene ETS2, Protein C-ets-2, v ets avian erythroblastosis virus E2 oncogene homolog 2, V ets avian erythroblastosis virus E26 oncogene homolog 2,ETS2 (Transcription Factor)
Cellular localisation: Nucleus. - Molecular Weight
- 52kDa
- Gene ID
- 2114, 644231
- UniProt
- P15036
- Pathways
- EGFR Signaling Pathway, Myometrial Relaxation and Contraction
-