LYZ antibody (AA 18-147)

Catalog No. ABIN7126650

The Mouse Monoclonal anti-LYZ antibody has been validated for IHC (f). It is suitable to detect LYZ in samples from Human.

Quick Overview for LYZ antibody (AA 18-147) (ABIN7126650)

Target: LYZ (Lysozyme (LYZ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LYZ antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Product Details anti-LYZ Antibody

Binding Specificity: AA 18-147

Specificity: Lysozyme is an enzyme, commonly referred to as the body s own antibiotic since it kills bacteria.Natural substrate of lysozyme is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species.Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. This antibody labels myeloid cells, histiocytes, granulocytes, macrophages and monocytes. It is helpful in the identification of myeloid or monocytic nature of acute leukemia.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human Lysozyme protein (around aa 18-147) (exact sequence is proprietary)

Isotype: IgG1

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human tonsil, spleen, lung or kidney.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for LYZ

Target: LYZ (Lysozyme (LYZ))

Alternative Name: LYZ

Background: 1 4 beta N acetlymuramidase C, Lysozyme C, LYZ, LYM, Renal amyloidosis,Lysozyme (Histiocytoma & Monocytic Acute Leukemia Marker)
Cellular localisation: Secreted.

Molecular Weight: 17kDa

Gene ID: 4069, 524579

UniProt: P61626