Recombinant Mammaglobin A antibody

Catalog No. ABIN7126681

This anti-Mammaglobin A antibody is a Mouse Monoclonal antibody detecting Mammaglobin A in IHC (f). Suitable for Human.

Quick Overview for Recombinant Mammaglobin A antibody (ABIN7126681)

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mammaglobin A antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Product Details anti-Mammaglobin A Antibody

Specificity: Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80 % of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15 % of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human Mammaglobin (SCGB2A2) protein

Isotype: IgG1

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, MCF-7 or T47D cells. Human breast carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Mammaglobin A

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Alternative Name: SCGB2A2

Background: Mammaglobin-1 (MGB1), Mammaglobin-A, Secretoglobin family 2A member 2 (SCGB2A2), SG2A2, UGB2,Mammaglobin (SCGB2A2) (Breast Cancer Marker)
Cellular localisation: Cytoplasm

Molecular Weight: 10.5kDa

Gene ID: 4250, 46452

UniProt: Q13296