BCL2L2 antibody

Catalog No. ABIN7126898

This Mouse Monoclonal antibody specifically detects BCL2L2 in IP, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for BCL2L2 antibody (ABIN7126898)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-BCL2L2 Antibody

Specificity: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human full-length BCL2L2 protein

Isotype: IgG2b

Application Details

Application Notes:

Known_Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: PC-3, HEK293, HePG2, MCF-7 or U87 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: BCL2L2

Background: BCL-W, BCL2-L-2, BCLW, KIAA0271, PPP1R51,BCL2-like 2 (BCL2L2) / BCL-W
Cellular localisation: Cytoplasm. Mitochondrion membrane.

Molecular Weight: 22-30kDa

Gene ID: 599, 410026

UniProt: Q92843