ACOX1 antibody (AA 221-320)

Catalog No. ABIN708491

The Rabbit Polyclonal anti-ACOX1 antibody has been validated for WB and ELISA. It is suitable to detect ACOX1 in samples from Human.

Quick Overview for ACOX1 antibody (AA 221-320) (ABIN708491)

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ACOX1 Antibody

Binding Specificity: AA 221-320

Predicted Reactivity: Human,Mouse,Rat,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ACOX1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Alternative Name: ACOX1

Background:

Synonyms: ACOX1, ACOX1_HUMAN, AOX antibody Palmitoyl CoA oxidase, Palmitoyl-CoA oxidase, Peroxisomal acyl coenzyme A oxidase 1, Peroxisomal acyl-coenzyme A oxidase 1, SCOX, Straight chain acyl CoA oxidase, Straight-chain acyl-CoA oxidase.

Background: Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD), also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning.

Gene ID: 51

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process