Recombinant HNRNPC antibody
Quick Overview for Recombinant HNRNPC antibody (ABIN7127547)
Target
See all HNRNPC AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- HNRNPC Recombinant Monoclonal Antibody
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Purification
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human HNRNPC
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Isotype
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody
KO Validated HNRNPC Reactivity: Human WB, IF, IHC (p), ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (pSer260) antibodyHNRNPC Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC Reactivity: Human WB, ICC, FACS Host: Rabbit Monoclonal 23GB6125 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-250) antibodyHNRNPC Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4E8 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 279-306), (C-Term) antibodyHNRNPC Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB24645 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC Reactivity: Human, Rabbit, Cow, Dog, Pig, Horse, Monkey, Goat, Guinea Pig, Hamster WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 241-290) antibodyHNRNPC Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (Middle Region) antibodyHNRNPC Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Horse, Zebrafish (Danio rerio), Goat, Guinea Pig, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-142), (N-Term) antibodyHNRNPC Reactivity: Human, Rat, Mouse, Rabbit, Cow WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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Alternative Name
- HNRNPC
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Background
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Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671).
Aliases: Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
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UniProt
- P07910
Target
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