Histone H4 antibody (meLys20)

Catalog No. ABIN7127903

This Rabbit Polyclonal antibody specifically detects Histone H4 in WB, IF, ELISA, IP and ChIP. It exhibits reactivity toward Human.

Quick Overview for Histone H4 antibody (meLys20) (ABIN7127903)

Target: Histone H4

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

Product Details anti-Histone H4 Antibody

Binding Specificity: meLys20

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: A synthetic peptide corresponding to the amino terminus of histone H4 in which Lys20 is mono-methylated.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2000, IF:1:50-1:200, IP:1:50-1:200, ChIP:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Histone H4

Target: Histone H4

Background:

Background:

 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Aliases: H4; H4/n; H4F2; H4FN; FO108; HIST2H4