LAT2 antibody

Catalog No. ABIN7130064

Product Details anti-LAT2 Antibody

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAT2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human LAT2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:5000, IHC:1:10-1:50,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LAT2

Target: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Alternative Name: LAT2 (LAT2 Products)

Background:

Background: This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Aliases: HSPC046 antibody, LAB antibody, LAT2 antibody, Linker for activation of B cells antibody, Linker for activation of B-cells antibody, Linker for activation of T cells family member 2 antibody, Linker for activation of T cells transmembrane adaptor 2 antibody, Linker for activation of T-cells family member 2 antibody, Membrane associated adapter molecule antibody, Membrane-associated adapter molecule antibody, Non T cell activation linker antibody, Non-T-cell activation linker antibody, NTAL_HUMAN antibody, WBSCR 5 antibody, Wbscr15 antibody, Williams Beuren syndrome chromosome region 15 antibody, Williams Beuren syndrome chromosome region 5 antibody, Williams-Beuren syndrome chromosomal region 15 protein antibody, Williams-Beuren syndrome chromosomal region 5 protein antibody, WSCR5 antibody

UniProt: Q9GZY6

Pathways: Fc-epsilon Receptor Signaling Pathway, BCR Signaling