MCM8 antibody

Catalog No. ABIN7130205

The Rabbit Polyclonal anti-MCM8 antibody has been validated for WB and ELISA. It is suitable to detect MCM8 in samples from Human.

Quick Overview for MCM8 antibody (ABIN7130205)

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MCM8 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human MCM8

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCM8

Target: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Alternative Name: MCM8

Background:

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Aliases: C20orf154 antibody, dJ967N21.5 antibody, DNA helicase MCM8 antibody, DNA replication licensing factor MCM8 antibody, MCM8 antibody, MCM8_HUMAN antibody, MGC119522 antibody, MGC119523 antibody, MGC12866 antibody, MGC4816 antibody, Minichromosome maintenance 8 antibody, Minichromosome maintenance complex component 8 antibody, REC antibody

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA