TBC1D22A antibody

Catalog No. ABIN7131302

This Rabbit Polyclonal antibody specifically detects TBC1D22A in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for TBC1D22A antibody (ABIN7131302)

Target: TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D22A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-TBC1D22A Antibody

Purpose: TBC1D22A Antibody

Cross-Reactivity: Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human TBC1D22A

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TBC1D22A

Target: TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))

Alternative Name: TBC1D22A

Background:

Background: TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Aliases: TBC1D22A antibody, C22orf4 antibody, TBC1 domain family member 22A antibody

UniProt: Q8WUA7