TMEM123 antibody

Catalog No. ABIN7131392

This Rabbit Polyclonal antibody specifically detects TMEM123 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for TMEM123 antibody (ABIN7131392)

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM123 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-TMEM123 Antibody

Purpose: TMEM123 Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human TMEM123

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TMEM123

Target: TMEM123 (Transmembrane Protein 123 (TMEM123))

Alternative Name: TMEM123

Background:

Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Aliases: TMEM123 antibody, KCT3 antibody, PSEC0111 antibody, UNQ641/PRO1271 antibody, Porimin antibody, Keratinocytes-associated transmembrane protein 3 antibody, KCT-3 antibody, Pro-oncosis receptor inducing membrane injury antibody, Transmembrane protein 123 antibody

UniProt: Q8N131

Pathways: Regulation of Cell Size