BCR antibody

Catalog No. ABIN7137944

This Rabbit Polyclonal antibody specifically detects BCR in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for BCR antibody (ABIN7137944)

Target: BCR (Breakpoint Cluster Region (BCR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-BCR Antibody

Purpose: BCR (Ab-177) Antibody

Cross-Reactivity: Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around aa. 175~179 (P-F-Y-V-N) derived from Human Bcr.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BCR

Target: BCR (Breakpoint Cluster Region (BCR))

Alternative Name: BCR

Background:

Background: GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

Sattler M, et al. Mol Cell Biol. 1999 Nov, 19(11): 7473-7480.
Li S et al. EMBO J. 2001 Dec 3, 20(23): 6793-6804.
Million RP, et,al. Mol Cell Biol. 2004 Jun, 24(11): 4685-4695.
Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006, 281: 30907

Aliases: ALL antibody, bcr antibody, BCR/ABL FUSION GENE, INCLUDED antibody, BCR/FGFR1 chimera protein antibody, BCR/FGFR1 FUSION GENE, INCLUDED antibody, BCR/PDGFRA FUSION GENE, INCLUDED antibody, BCR_HUMAN antibody, BCR1 antibody, Breakpoint cluster region antibody, Breakpoint cluster region protein antibody, CML antibody, D22S11 antibody, D22S662 antibody, FGFR1/BCR chimera protein antibody, PHL antibody, Renal carcinoma antigen NY-REN-26 antibody

UniProt: P11274

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling