CRY1 antibody
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- Target See all CRY1 Antibodies
- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CRY1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Mouse
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1.
- Isotype
- IgG
- Top Product
- Discover our top product CRY1 Primary Antibody
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- Application Notes
- WB:1:500-1:3000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
- Alternative Name
- CRY1 (CRY1 Products)
- Background
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Background:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
Morioka N,et al. (2010) J Pharmacol Sci.113(3):234-45.
Fonseca F,et al. (2010) Mol Diagn Ther.14(3):171-8.
Stratmann M,et al.(2010) Genes Dev.24(12):1317-28.Aliases: Cry1 antibody, CRY1_HUMAN antibody, Cryptochrome 1 (photolyase like) antibody, Cryptochrome 1 antibody, Cryptochrome-1 antibody, PHLL1 antibody, Photolyase 1 antibody, Photolyase-like antibody
- UniProt
- Q16526
- Pathways
- Response to Water Deprivation, Proton Transport
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