Girdin antibody (pSer417)

Catalog No. ABIN7138609

This anti-Girdin antibody is a Rabbit Polyclonal antibody detecting Girdin in ELISA and IHC. Suitable for Human.

Quick Overview for Girdin antibody (pSer417) (ABIN7138609)

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Girdin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Girdin Antibody

Binding Specificity: pSer417

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 417(L-E-M(p)-A-Q) derived from Human Girdin .

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Girdin

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Alternative Name: CCDC88A

Background:

Background:

girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.

Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).

Aliases: AKT iphosphorylation enhancer antibody, Akt phosphorylation enhancer antibody, APE antibody, Ccdc88a antibody, Coiled coil domain containing 88A antibody, Coiled coil domain containing protein 88A antibody, Coiled-coil domain-containing protein 88A antibody, FLJ10392 antibody, G alpha interacting vesicle associated protein antibody, G alpha-interacting vesicle-associated protein antibody, Galpha interacting vesicle associated protein antibody, Girders of actin filament antibody, Girdin antibody, GIV antibody, GRDN antibody, GRDN_HUMAN antibody, HkRP1 antibody, Hook related protein 1 antibody, Hook-related protein 1 antibody, KIAA1212 antibody

UniProt: Q3V6T2