SYT1 antibody (pThr202)

Catalog No. ABIN7138798

This anti-SYT1 antibody is a Rabbit Polyclonal antibody detecting SYT1 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for SYT1 antibody (pThr202) (ABIN7138798)

Target: SYT1 (Synaptotagmin I (SYT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SYT1 Antibody

Binding Specificity: pThr202

Purpose: Phospho-SYT1 (Thr202) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 202(R-K-T(p)-L-N) derived from Human Synaptotagmin.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Alternative Name: SYT1

Background:

Background:

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.

E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001, 36: 107.
Gry Houeland, J Neurophysiol, Jan 2007, 97: 134 - 143.
Christelle Carteron, J. Cell Sci., Mar 2006, 119: 898 - 909.
Vladimir I. Slepnev, Science, Aug 1998, 281: 821.

Aliases: DKFZp781D2042 antibody, FLJ42519 antibody, p65 antibody, SVP65 antibody, Synaptotagmin 2 antibody, Synaptotagmin I antibody, Synaptotagmin II antibody, Synaptotagmin-1 antibody, SYT antibody, Syt1 antibody, SYT1_HUMAN antibody, Syt2 antibody, SytI antibody

UniProt: P21579

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport