SP1 antibody (pThr739)
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- Target See all SP1 Antibodies
- SP1 (Sp1 Transcription Factor (SP1))
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Binding Specificity
- pThr739
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Human, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of threonine 739 (T-A-T(p)-P-S) derived from Human SP1
- Isotype
- IgG
- Top Product
- Discover our top product SP1 Primary Antibody
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anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibodySP1 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB17350 unconjugated
anti-Sp1 Transcription Factor (SP1) (C-Term) antibodySP1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1A5 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibodySP1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4B11 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) antibodySP1 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Monoclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (pThr739) antibodySP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibodySP1 Reactivity: Human, Mouse WB, ELISA, IF Host: Mouse Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibodySP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SP1 (Sp1 Transcription Factor (SP1))
- Alternative Name
- SP1 (SP1 Products)
- Background
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Background: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-a G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Thiesen HJ,et al.(1990)Nucleic Acids Res.18(11):3203-9.
Zutter MM,et al.(1997) Blood.90(2):678-89.
Lou Z,et al.(2005)Cancer Res.65(3):1007-17Aliases: SP 1 antibody, SP1 antibody, Sp1 transcription factor antibody, SP1_HUMAN antibody, Specificity protein 1 antibody, Transcription factor Sp1 antibody, TSFP 1 antibody, TSFP1 antibody
- UniProt
- P08047
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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