Calmodulin 1 antibody (pSer81, pThr79)

Catalog No. ABIN7138901

This Rabbit Polyclonal antibody specifically detects Calmodulin 1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Calmodulin 1 antibody (pSer81, pThr79) (ABIN7138901)

Target: Calmodulin 1 (Calm1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calmodulin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Calmodulin 1 Antibody

Binding Specificity: pSer81, pThr79

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine79/serine81(K-D-T(p)-D-S(p)-E-E) derived from Human Calmodulin .

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Calmodulin 1

Target: Calmodulin 1 (Calm1)

Alternative Name: CALM1

Background:

Background:

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.

Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76
Arrigoni G, et al. (2004) Biochemistry 43, 12788-98
Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70

Aliases: CALM, CALM1, CALM2, CALM3, CAM

UniProt: P62158

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling