TUBA1A antibody (pTyr272)

Catalog No. ABIN7138966

This anti-TUBA1A antibody is a Rabbit Polyclonal antibody detecting TUBA1A in ELISA and WB. Suitable for Human.

Quick Overview for TUBA1A antibody (pTyr272) (ABIN7138966)

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA1A antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TUBA1A Antibody

Binding Specificity: pTyr272

Purpose: Phospho-TUBA1A/TUBA1B/TUBA1C/TUBA3C/TUBA3E/TUBA4A (Tyr272) Antibody

Cross-Reactivity: Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 272 (A-T-Y(p)-A-P) derived from Human TUBA1/3/4.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TUBA1A

Target: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Alternative Name: TUBA1A

Background:

Background:

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.

Adler A.J., Bioorg. Med. Chem. 9:1967-1976(2001).
Sugano S., Nat. Genet. 36:40-45(2004).
Venter J.C., Submitted (JUL-2005).

Aliases: Alpha tubulin 3 antibody, Alpha-tubulin 3 antibody, B alpha 1 antibody, FLJ25113 antibody, LIS3 antibody, TBA1A_HUMAN antibody, TUBA1A antibody, TUBA3 antibody, Tubulin alpha 1a antibody, Tubulin alpha 1A chain antibody, Tubulin alpha 3 antibody, Tubulin alpha 3 chain antibody, Tubulin alpha brain specific antibody, Tubulin alpha-1A chain antibody, Tubulin alpha-3 chain antibody, Tubulin B alpha 1 antibody, Tubulin B-alpha-1 antibody

UniProt: Q71U36

Pathways: Microtubule Dynamics, M Phase