Cofilin1/2 (CFL1/2) (pTyr88) antibody
Quick Overview for Cofilin1/2 (CFL1/2) (pTyr88) antibody (ABIN7139084)
Target
See all Cofilin1/2 (CFL1/2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pTyr88
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Cross-Reactivity
- Human, Mouse
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Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogen
- Peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y(p)-E-T) derived from Human coflin1/cofilin2.
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Isotype
- IgG
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anti-Cofilin1/2 (CFL1/2) (Internal Region) antibody
CFL1/2 Reactivity: Human WB, IF, ELISA Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB:1:500-1:1000, IHC:1:50-1:100,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cofilin1/2 (CFL1/2)
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Alternative Name
- CFL1/CFL2
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Background
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Background: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830.
Arber, S. et al. (1998) Nature 393, 805-809.
Yang, N. et al. (1998) Nature 393, 809-812.Aliases: CFL1/CFL2
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UniProt
- P23528, Q9Y281
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Pathways
- Tube Formation, CXCR4-mediated Signaling Events
Target
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