MEST antibody
Quick Overview for MEST antibody (ABIN7140340)
Target
See all MEST AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Pig, Rabbit
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Purification
- Affinity purified
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Immunogen
- Purified recombinant human PEG10 protein fragments expressed in E.coli.
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Isotype
- IgG1, IgG1 kappa
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Application Notes
- Recommended dilution:WB:1:500-1:5000,IP:1:200-1:2000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MEST (Mesoderm Specific Transcript (MEST))
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Alternative Name
- PEG1
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Background
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Background: This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.
Aliases: EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3
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UniProt
- Q86TG7
Target
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