Dystonin antibody
Quick Overview for Dystonin antibody (ABIN7141251)
Target
See all Dystonin (DST) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Cross-Reactivity
- Human
-
Purification
- Protein G purified
-
Immunogen
- Recombinant DST Protein
-
Isotype
- IgG1, IgG1 kappa
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Dystonin (DST)
-
Alternative Name
- DST
-
Background
-
Background: This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
Aliases: Dystonin,Bullous pemphigoid antigen,BPA
-
UniProt
- Q03001
Target
-