PdeH (AA 1-255) antibody (Biotin)

Catalog No. ABIN7141443

The Rabbit Polyclonal anti- antibody has been validated for ELISA. It is suitable to detect in samples from E. coli.

Quick Overview for PdeH (AA 1-255) antibody (Biotin) (ABIN7141443)

Target: PdeH

Reactivity: E. coli

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: ELISA

Product Details

Binding Specificity: AA 1-255

Cross-Reactivity: E. coli

Purification: >95%, Protein G purified

Immunogen: Recombinant Escherichia coli Cyclic di-GMP phosphodiesterase PdeH protein (1-255AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: PdeH

Background:

Background: Involved in the control of the switch from cell motility to adhesion via regulation of cellular levels of cyclic-di-GMP (c-di-GMP) (PubMed:18765794). Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcEPdeH pair (module I) regulates the activity of the DgcMPdeR pair (module II), which in turn regulates activity of the transcription factor MlrA and expression of the master biofilm regulator csgD (PubMed:23708798). Effect on flagella is controlled via the c-di-GMP-binding flagellar brake protein YcgR (PubMed:18765794).

Aliases: pdeH antibody, yhjH antibody, b3525 antibody, JW3493 antibody, Cyclic di-GMP phosphodiesterase PdeH antibody, EC 3.1.4.52 antibody

UniProt: P37646