HEV ORF3 antibody (AA 1-114) (Biotin)

Catalog No. ABIN7141955

This Rabbit Polyclonal antibody specifically detects HEV ORF3 in ELISA. It exhibits reactivity toward Hepatitis E Virus (HEV).

Quick Overview for HEV ORF3 antibody (AA 1-114) (Biotin) (ABIN7141955)

Target: HEV ORF3 (Hepatitis E Virus ORF3 (HEV ORF3))

Reactivity: Hepatitis E Virus (HEV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEV ORF3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-HEV ORF3 Antibody (Biotin)

Binding Specificity: AA 1-114

Cross-Reactivity: Hepatitis E Virus (HEV)

Purification: >95%, Protein G purified

Immunogen: Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HEV ORF3

Target: HEV ORF3 (Hepatitis E Virus ORF3 (HEV ORF3))

Alternative Name: ORF3

Target Type: Viral Protein

Background:

Background: Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways.

Aliases: ORF3 antibody, Protein ORF3 antibody, pORF3 antibody

UniProt: O90299