Hepatitis E Virus ORF3 (HEV-1 ORF3) (AA 1-114) antibody (HRP)

Catalog No. ABIN7141957

This anti- antibody is a Rabbit Polyclonal antibody detecting in ELISA. Suitable for Hepatitis E Virus (HEV).

Quick Overview for Hepatitis E Virus ORF3 (HEV-1 ORF3) (AA 1-114) antibody (HRP) (ABIN7141957)

Target: Hepatitis E Virus ORF3 (HEV-1 ORF3)

Reactivity: Hepatitis E Virus (HEV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Product Details

Binding Specificity: AA 1-114

Purpose: ORF3 Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Hepatitis E Virus ORF3 (HEV-1 ORF3)

Alternative Name: Hepatitis E virus genotype 1 ORF3

Target Type: Viral Protein

Background:

Background: Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways.

Aliases: ORF3 antibody, Protein ORF3 antibody, pORF3 antibody

UniProt: O90299