APOC1 antibody (AA 35-48) (Biotin)
Quick Overview for APOC1 antibody (AA 35-48) (Biotin) (ABIN7144416)
Target
See all APOC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 35-48
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Apolipoprotein C-I protein (35-48aa)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APOC1 (Apolipoprotein C-I (APOC1))
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Alternative Name
- APOC1
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Background
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Background: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10 % of the protein of the VLDL and 2 % of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
Aliases: Apolipoprotein C-I (Apo-CI) (ApoC-I) (Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I], APOC1
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UniProt
- P02654
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Pathways
- Apoptosis
Target
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