AHRR antibody (AA 255-506)

Catalog No. ABIN7144661

This Rabbit Polyclonal antibody specifically detects AHRR in ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for AHRR antibody (AA 255-506) (ABIN7144661)

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AHRR antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-AHRR Antibody

Binding Specificity: AA 255-506

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Aryl hydrocarbon receptor repressor protein (255-506AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Alternative Name: AHRR

Background:

Background: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Aliases: AHH antibody, AhR repressor antibody, AhRR antibody, AHRR_HUMAN antibody, aryl hydrocarbon hydroxylase regulator antibody, aryl hydrocarbon receptor regulator antibody, Aryl hydrocarbon receptor repressor antibody, Arylhydrocarbon receptor repressor antibody, bHLHe77 antibody, Class E basic helix-loop-helix protein 77 antibody, Dioxin receptor repressor antibody, KIAA1234 antibody, MGC167813 antibody, MGC176630 antibody, OTTHUMP00000221488 antibody, OTTHUMP00000221489 antibody

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha