BANF1 antibody (AA 2-89)

Catalog No. ABIN7145258

This Rabbit Polyclonal antibody specifically detects BANF1 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for BANF1 antibody (AA 2-89) (ABIN7145258)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BANF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BANF1 Antibody

Binding Specificity: AA 2-89

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Barrier-to-autointegration factor protein (2-89AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Alternative Name: BANF1

Background:

Background: Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.

Aliases: BAF antibody, BAF_HUMAN antibody, BANF 1 antibody, BANF1 antibody, Barrier to autointegration factor 1 antibody, Barrier to autointegration factor antibody, Barrier-to-autointegration factor antibody, BCRG 1 antibody, BCRG1 antibody, BCRP 1 antibody, BCRP1 antibody, Breakpoint cluster region protein 1 antibody, D14S1460 antibody, MGC111161 antibody, NGPS antibody

UniProt: O75531