BAAT antibody (AA 313-400)

Catalog No. ABIN7145589

The Rabbit Polyclonal anti-BAAT antibody has been validated for ELISA, IHC and IF. It is suitable to detect BAAT in samples from Human.

Quick Overview for BAAT antibody (AA 313-400) (ABIN7145589)

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAAT antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BAAT Antibody

Binding Specificity: AA 313-400

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Bile acid-CoA:amino acid N-acyltransferase protein (313-400AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BAAT

Target: BAAT (Bile Acid CoA: Amino Acid N-Acyltransferase (Glycine N-Choloyltransferase) (BAAT))

Alternative Name: BAAT

Background:

Background: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.

Aliases: FLJ20300 antibody, BAAT antibody, BAAT_HUMAN antibody, BACAT antibody, BAT antibody, Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody, Bile acid CoA:amino acid N acyltransferase antibody, Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody, Bile acid Coenzyme A: amino acid N acyltransferase antibody, Bile acid-CoA:amino acid N-acyltransferase antibody, Glycine N choloyltransferase antibody, Glycine N-choloyltransferase antibody, Long chain fatty acyl CoA hydrolase antibody, Long-chain fatty-acyl-CoA hydrolase antibody, MGC104432 antibody

UniProt: Q14032