CATSPER4 antibody (AA 306-472) (Biotin)
Quick Overview for CATSPER4 antibody (AA 306-472) (Biotin) (ABIN7147036)
Target
See all CATSPER4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 306-472
-
Cross-Reactivity
- Human
-
Purification
- >95%, Protein G purified
-
Immunogen
- Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
-
Isotype
- IgG
-
-
anti-Cation Channel, Sperm Associated 4 (CATSPER4) (AA 306-472) antibody
CATSPER4 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
-
Alternative Name
- CATSPER4
-
Background
-
Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .
Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody
-
UniProt
- Q7RTX7
Target
-
